Distribution of interstitial lung diseases in a tertiary care center of South India

Mahesh Babu Vemuri, Manju Rajaram, Madhusmita Mohanty Mohapatra, Mathavaswami Vijayageetha, V. S. Negi, Subathra Adithan, Pampa Chtoi, B. V. Sai Chandran, Ravindrachari M

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Aim: Find the distribution of interstitial lung disease (ILD) subtypes in a tertiary care center.

Methods: A descriptive study was conducted between August 2016 and November 2018 in a tertiary care center in Puducherry, South India. Baseline demographic details, clinical symptoms, signs, radiological findings (chest radiograph and HRCT), pathological findings, and physiological findings were taken into consideration and a diagnosis of the type of interstitial lung disease was made using multidisciplinary discussion. Statistical analysis was done using SPSS 19.0 version.

Results: A total of 150 patients were recruited of which 70.5% were females. The most common ILD subtype in our study was connective tissue disease-associated ILD – 97 patients (65%) followed by idiopathic pulmonary fibrosis (IPF)–31 patients (22%). The most common type of CTD ILD observed in our study was progressive systemic sclerosis (46%) followed by mixed connective tissue disease (24%). The most common HRCT finding was the NSIP pattern and the most commonly observed physiological abnormality was moderate restriction and moderate diffusion impairment.

Conclusion: Connective tissue disease-associated ILD was the most common ILD found in our study amongst the south Indian population. This suggests that the distribution of ILD would vary depending on the geographical area and the environmental exposure which was in contrast with the Indian ILD registry.

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